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Detection of mouth alcohol during breath alcohol analysis.
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Författare/Namn
Titel
  • Detection of mouth alcohol during breath alcohol analysis.
Förlag, etc.
  • Elsevier BV, 2015
Utgivningsår
  • 2015
Anmärkning: Innehållsbeskrivning, sammanfattning
  • The presence of mouth alcohol (MA) during alcohol breath test for law enforcement is the most common cause of falsely high breath alcohol concentrations (BrAC). A fast and reliable test for detection of MA roadside at the scene of the act would facilitate the police efforts for proper prosecution. A tentative technique to use orally exhaled water vapour as a reference gas to position the origin of alcohol was validated. BrAC and water vapour concentration (WVC) were simultaneously measured as a known MA component was added to subjects with existing blood alcohol. In the absence of MA, water always precedes alcohol in a volumetric expirogram. In the presence of MA this relationship reversed. A scatterplot of WVC versus BrAC from similar fractional exhaled volumes illustrates how their relative positions change by MA. A deviation area (DA) between the scatterplot curve and a fictitious linear relationship was defined as a measurement of MA. The accuracy and cut-off level of the DA to detect MA were determined with receiver operating characteristic (ROC) curve analysis. The area under the ROC curve (AUC) was 0.95 (95% CI 0.90-1.0), indicating excellent discriminatory ability. The optimal cut-off for DA to discriminate between MA ≥0.010mg/L (1μg/100ml, 0.002g/210L) or lack of MA was -0.35, with a sensitivity of 0.91 and specificity of 0.95. Analysis of BrAC in relation to WVC is a practical method to detect and confirm MA contamination with high reliability.
Ämnesord
Ämnesord
Medarbetare
Institution
  • Anestesiologi och intensivvård. Sektion II
Värdpublikation
  • Forensic Science International. ISSN 1872-6283 ; 249, s. 66-72
Antal i kö:
  • 0 (0)
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*008160401s2015    |  |||||||||||000 ||eng| 
*0247 $ahttps://lup.lub.lu.se/record/5143829$2URI
*0247 $ahttps://doi.org/10.1016/j.forsciint.2015.01.017$2DOI
*035  $a(SwePub)oai:lup.lub.lu.se:36a30a9b-5276-4f16-9db7-c8b1aac6206c
*041  $aeng$beng
*1001 $aLindberg, Lars$0(Swepub:lu)anes-lli
*24510$aDetection of mouth alcohol during breath alcohol analysis.
*264 1$bElsevier BV,$c2015
*520  $aThe presence of mouth alcohol (MA) during alcohol breath test for law enforcement is the most common cause of falsely high breath alcohol concentrations (BrAC). A fast and reliable test for detection of MA roadside at the scene of the act would facilitate the police efforts for proper prosecution. A tentative technique to use orally exhaled water vapour as a reference gas to position the origin of alcohol was validated. BrAC and water vapour concentration (WVC) were simultaneously measured as a known MA component was added to subjects with existing blood alcohol. In the absence of MA, water always precedes alcohol in a volumetric expirogram. In the presence of MA this relationship reversed. A scatterplot of WVC versus BrAC from similar fractional exhaled volumes illustrates how their relative positions change by MA. A deviation area (DA) between the scatterplot curve and a fictitious linear relationship was defined as a measurement of MA. The accuracy and cut-off level of the DA to detect MA were determined with receiver operating characteristic (ROC) curve analysis. The area under the ROC curve (AUC) was 0.95 (95% CI 0.90-1.0), indicating excellent discriminatory ability. The optimal cut-off for DA to discriminate between MA ≥0.010mg/L (1μg/100ml, 0.002g/210L) or lack of MA was -0.35, with a sensitivity of 0.91 and specificity of 0.95. Analysis of BrAC in relation to WVC is a practical method to detect and confirm MA contamination with high reliability.
*650  $aAlkoholprov
*653  $aPolForsKart
*653  $aForensik
*7001 $aGrubb, David$uLund University,Lunds universitet,Anestesiologi och intensivvård,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Anesthesiology and Intensive Care,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine$4aut$0(Swepub:lu)med-dgr
*7001 $aDencker, Daniel$4aut
*7001 $aFinnhult, Mikael$4aut
*7001 $aOlsson, Sven-Gunnar$4aut
*7102 $aAnestesiologi och intensivvård.$bSektion II
*7730 $tForensic Science International.$x1872-6283 ;$g249, s. 66-72
*8564 $uhttp://dx.doi.org/10.1016/j.forsciint.2015.01.017$yFulltext
*85648$uhttps://lup.lub.lu.se/record/5143829$yPublikationen på LU:s webbplats
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